Ultrafast MRI. Chemical-shift resolved flow imaging inside a complex microfluidic device. Using remote detection, in which the magnetization is detected outside the sample, the effects of field inhomogeneity are largely eliminated. Harel et al. JMR 2008 (Pines Lab, UC- Berkeley)
Time-of-flight imaging. Using Xenon gas as a sensitive sensor of its environment, magnetic resonance can distinguish nanometer-size pores in silica aerogel even when the spatial resolution is far too poor. Non-invasive time-resolved imaging indicates at least two pore regimes with very different transport properties. Harel et al. Nat. Mat. 2006 (Pines Lab, UC- Berkeley)
Imaging flow in a lab-on-chip device. Water and ethanol pass through different channels of a simple T-chip device. Magnetic resonance can differentiate the two liquids based solely on their different chemical-shift signatures. Zooming in on the mixing region reveals that at these low Reynolds numbers, the fluids do not effectively mix. Harel et al. Phys. Rev. Lett. 2007 (Pines Lab, UC- Berkeley)
Remote Detection. Experimental setup for remote detection. Two probes are used - one for encoding and the other for sensitive detection. (Pines Lab, UC- Berkeley)
Microcoil NMR. Home-built remote detection probe showing tank circuit (left) and wound microsolenoid coil (above). The coil is immersed in a perfluorinate compound to improve spectral resolution by susceptibility matching the solvent to the surrounding (Pines Lab, UC- Berkeley)
Single-shot 2D Photon Echo Spectroscopy (GRAPES). Left: CCD image created by interfering the photon echo signal with a local oscillator pulse. All the coherence times (vertical axis) are sampled simultaneously. Right: Resultant 2D rephasing spectra of IR 144 at T = 0 after Fourier transformation of the interferogram on the left. Harel et al. JCP A 2011; Harel et al. PNAS 2010 (Engle Lab, UChicago)
Experimental Setup. Optical layout of GRadient-Assisted Photon Echo Spectroscopy (GRAPES). i. Generation of four pulses. ii. GRAPES mirror assembly. iii. Sample showing line of focus. iv. phase-matching geometry. (Engle Lab, UChicago)
