Our research interests are focused on the chemistry of life sciences with an emphasis on coordination chemistry, bioinorganic chemistry, biological imaging and the development of electronic biosensors. The specific topics of research and subgroups of the lab include:
Biological Molecular Imaging:
Design and synthesis of spectroscopic and magnetic probes that incorporate
novel functionality for magnetic resonance and fluorescent in vivo microscopic
imaging of biological systems with particular emphasis on nerve patterning,
regulation of cell lineage, gene expression and DNA transfection.
Weak Interactions In Ligand-Receptor Binding:
Using transition metal probes to study long-range electronic coupling through
pi-stacked unsaturated systems, proteins, and the development of electronic
DNA and protein biosensors.
Metal Complexes As Enzyme Inhibitors:
Investigate the interaction of small molecule transition metal complexes as
enzyme inhibitors for the development of therapeutic antitumor and antiviral
drugs.