Professor Raanan Carmieli

Education | Research Description | Publications | Group Home

Northwestern University
2190 Campus Drive
Evanston, IL 60208 USA

E-mail:
r-carmielli[at]northwestern.edu

Research Assistant Professor at Northwestern University,
Department of Chemistry and the Argonne-Northwestern Solar Energy Research (ANSER).
The work focuses on instrumentation and methodologies development in magnetic resonance for the study of photoexcited systems.

 

Previous Employment

2006–2010 Northwestern University, Evanston IL
Post Doctoral Fellow
Host: Prof. Michael R. Wasielewski
Application of EPR spectroscopy to photo–excited systems.

2005–2006 InSight Biopharmaceuticals Ltd 
R&D Project leader

Education

2000-2005 Ph. D. Weizmann Institute of Science, Rehovot, Israel
Supervisor: Daniella Goldfarb
Thesis Subject: Investigation of transition metal sites in Metalloproteins, and peptide membrane interaction using advanced EPR and ENDOR Techniques

1998-2000 M. Sc. Weizmann Institute of Science, Rehovot, Israel 
Supervisor: Daniella Goldfarb
Thesis Subject :Investigation of Mn(II) metal sites in Concanavalin A by W-band Pulsed EPR and ENDOR techniques

1994 – 1997 B. Sc. Faculty of Exact Sciences, Bar-Ilan University

Research Description

Time resolved EPR (TREPR) is a well-established method for measuring radical pair (RP) and triplet states in a donor – acceptor systems. The experiment constitute the application of a laser pulse and then the measurement is carried out using continuous microwave (CW) or through a series of microwave pulses for the detection of the polarized EPR signal. While optical spectroscopy has a clear advantage concerning the obtainable time resolution down to the femtosecond regime, the coupling of the reduction and oxidation is generally only visible in parallel kinetics of the component in the absorbance – difference spectra belonging to the two different redox partners. In contrast, TREPR suffers from a comparatively low time resolution of presently 10 ns but has a clear advantage of a direct observation of the coupling between the redox partners. This is due to the sensitivity of the magnetic resonance method to weak interactions that cannot be resolved by optical techniques on large molecules.

Recently we have published our study on structure and dynamics of photogenerated triplet radical ion pairs in DNA hairpins (AqGn) possessing a tethered anthraquinone (Aq) end-capping group. The TREPR spectra of the 3(Aq-•Gn+•) radical ion pairs showed strong dependence on their spin-spin dipolar interaction and weakly on their spin-spin exchange coupling. The anisotropy of 3(Aq-•Gn+•) made it possible to determine that the π systems of Aq-• and G+• within the radical ion pair are parallel to one another.

fig 1  

At the present we focus on applying modern pulse EPR technique such as out-of-phase ESEEM, ESEEM and ENDOR on donor – acceptor and self assembled system in order to better characterize them electronically and structurally.

fig 1    

In addition, we have designed and constructed a window-interfaced EPR simulation package for simulating and fitting EPR data using MATLAB. The program was designed and constructed by Raanan Carmieli from various codes we had in our group written by Dr. Qixi Mi, Dr. Zachary E. Dance and Dr. Raanan Carmieli. Useful help was given by Dr. Chul Hoon Kim. The program is free for download and it is an open code so feel free to test, check the code and send us your comment for improvement. We continue to improve and add new features all the time. Currently we are working on adding ENDOR simulation and speed up calculation time by parallel computing. If you use this program please don’t forget to acknowledge us.

Publications

Jason M. Spruell, Ali Coskun, Douglas C. Friedman, Ross S. Forgan, Amy A. Sarjeant, Ali Trabolsi, Albert C. Fahrenbach, Gokhan Barin, Walter F. Paxton, Sanjeev K. Dey, Mark A. Olson, Diego Benı´tez, Ekaterina Tkatchouk, Michael T. Colvin, Raanan Carmielli, Stuart T. Caldwell, Georgina M. Rosair, Shanika Gunatilaka Hewage, Florence Duclairoir, Jennifer L. Seymour, Alexandra M. Z. Slawin, William A. Goddard III, Michael R. Wasielewski, Graeme Cooke and J. Fraser Stoddart; Highly stable tetrathiafulvalene radical dimers in [3]catenanes. Nature Chemistry 2010, 2, 870-879.

Gokhan Barin, Ali Coskun, Douglas C. Friedman, Mark A. Olson, Michael T. Colvin, Raanan Carmielli, Sanjeev K. Dey, O. Altan Bozdemir, Michael R. Wasielewski, J. Fraser Stoddart; A Multistate Switchable [3]Rotacatenane. Chem. Eur. J. 2011, 17, 213-222.

Michael T. Colvin, Annie Butler Ricks, Amy M. Scott, Amanda L. Smeigh, Raanan Carmieli, Tomoaki Miura, and Michael R. Wasielewski; Magnetic Field-Induced Switching of the Radical-Pair Intersystem Crossing Mechanism in a Donor-Bridge-Acceptor Molecule for Artificial Photosynthesis. J. Am. Chem. Soc. 2011, 133, 1240-1243.

Ali Coskun, Jason M. Spruell, Gokhan Barin, Albert C. Fahrenbach, Ross S. Forgan, Michael T. Colvin, Raanan Carmieli, Diego Bentez, Ekaterina Tkatchouk, Douglas C. Friedman, Amy A. Sarjeant, Michael R. Wasielewski, William A. Goddard, III, and J. Fraser Stoddar; Mechanically Stabilized Tetrathiafulvalene Radical Dimers. J. Am. Chem. Soc. 2011, 133, 4538–4547.

Jonathan C. Barnes, Albert C. Fahrenbach, Scott M. Dyar, Marco Frasconi, Marc A. Giesener, Zhixue Zhu, Zhichang Liu, Karel J. Hartlieb, Raanan Carmieli, Michael R. Wasielewski, and J. Fraser Stoddart; Mechanically induced intramolecular electron transfer in a mixed-valence molecular shuttle. Proc. Natl. Acad. Sci. 2012, 109, 11546-11551.

Zhixue Zhu; Albert C. Fahrenbach; Hao, Li; Jonathan C. Barnes; Zhichang Liu; Scott M. Dyar; Huacheng, Zhang; Juying, Lei; Raanan, Carmieli; Amy, Sarjeant; Charlotte, Stern; Michael R. Wasielewski; J. Fraser Stoddart; Controlling Switching in Bistable [2]Catenanes by Combining Donor-Acceptor and Radical-Radical Interactions. J. Am. Chem. Soc.2012, accepted.

Raanan Carmieli, Amanda L. Smeigh, Sarah M. Mickley Conron, Arun K. Thazhathveetil, Masaaki Fuki, Yasuhiro Kobori, Frederick D. Lewis, and Michael R. Wasielewski; Structure and Dynamics of Photogenerated Triplet Radical Ion Pairs in DNA Hairpin Conjugates with Anthraquinone End Caps. J. Am. Chem. Soc. 2012, 10.1021/ja303721j.

Jonathan C. Barnes, Albert C. Fahrenbach, Dennis Cao, Scott M. Dyar, Marco Frasconi, Marc A. Giesener, Diego Benítez, Ekaterina Tkatchouk, Weon Ho Shin, Hao Li, Charlotte L. Stern, Amy A. Sarjeant, Karel J. Hartlieb, Zhichang Liu, Raanan Carmieli, Youssry Y. Botros, Jang Wook Choi, Alexandra M.Z. Slawin, Michael R. Wasielewski, William A. Goddard III, J. Fraser Stoddart1; A Radically Configurable Six-State Compound. Science 2012, Submitted.

Lukas, Kobr; Daniel, Gardner; Amanda L. Smeigh; Scott M. Dyar; Steven Karlen; Raanan Carmieli; Michael R. Wasielewski; Fast Photo-driven Electron Spin Coherence Transfer: A Quantum Gate Based on a Spin Exchange J-Jump. J. Am. Chem. Soc. 2012, accepted.

Time-resolved EPR studies of charge recombination and triplet-state formation within donor-bridge-acceptor molecules having wire-like oligofluorene bridges. Miura, Tomoaki; Carmieli, Raanan; Wasielewski, Michael R., Journal of Physical Chemistry A  (2010),  114(18),  5769-5778. 

Photoinitiated Charge Transport through p -Stacked Electron Conduits in Supramolecular Ordered Assemblies of Donor-Acceptor Triads. Bullock, Joseph E.; Carmieli, Raanan; Mickley, Sarah M.; Vura-Weis, Josh; Wasielewski, Michael R., Journal of the American Chemical Society  (2009),  131(33),  11919-11929.

Direct Measurement of Photoinduced Charge Separation Distances in Donor-Acceptor Systems for Artificial Photosynthesis Using OOP-ESEEM.    Carmieli, Raanan; Mi, Qixi; Butler Ricks, Annie; Giacobbe, Emilie M.; Mickley, Sarah M.; Wasielewski, Michael R., Journal of the American Chemical Society  (2009),  131(24),  8372-8373.

Excited State, Charge Transfer, and Spin Dynamics in DNA Hairpin Conjugates with Perylenediimide Hairpin Linkers. Carmieli, Raanan; Zeidan, Tarek A.; Kelley, Richard F.; Mi, Qixi; Lewis, Frederick D.; Wasielewski, Michael R., Journal of Physical Chemistry A  (2009),  113(16),  4691-4700.

Charge-Transfer and Spin Dynamics in DNA Hairpin Conjugates with Perylenediimide as a Base-Pair Surrogate. Zeidan, Tarek A.; Carmieli, Raanan; Kelley, Richard F.; Wilson, Thea M.; Lewis, Frederick D.; Wasielewski, Michael R., Journal of the American Chemical Society  (2008),  130(42),  13945-13955.