 | |
Honors and Other Professional
Activities:
 |
Pharmaceutical Inventions |
| |
 |
Inventor of LyricaTM (pregabalin), marketed worldwide for the treatment of epilepsy, neuropathic pain, fibromyalgia, and (in Europe) for generalized anxiety disorder. |
|
Editorial
Boards
|
|
Scientific Advisory Boards
|
Influx, Inc. 1998-present
|
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Protez Pharmaceuticals, Inc. 2004-
|
|
SynChem, Inc. 2004-
|
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University of Illinois, Chicago, NIH Anthrax Project 2006 |
|
University of Illinois, Chicago, NIH SARS Project 2007 |
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Cambria Pharmaceuticals LLC 2007- |
|
|
International Advisory Committees
|
10th
International Amine Oxidase Workshop 8/2002
(Istanbul, Turkey)
|
|
XVIIIth International Symposium on
Medicinal Chemistry (Copenhagen, Denmark) 9/2004
|
|
|
National
Offices Held
|
Elected
Office: Program Chair, Division of Biological Chemistry,
ACS 2001
|
|
Member,
Long-Range Planning Committee for the Division of Medicinal
Chemistry, ACS 1999-2002
|
|
Elected
Office: Treasurer, Division of Biological Chemistry,
American Chemical Society 1993-1996
|
|
Elected
Office: Nominating Committee, Division of Biological
Chemistry of the American Chemical Society 1990
|
|
Elected
Office: Program Chair, Division of Biological Chemistry, ACS
2001
|
|
Member,
Canvassing Committee for the American Chemical
Society Alfred Burger Award in Medicinal
Chemistry 1982-1987
|
|
Chairman
1986-1987
|
|
Member,
American Chemical Society Organic
Chemistry Examination Committee 1986
|
|
Member,
Long-Range Planning Committee for the Division
of Medicinal Chemistry 1999-2002
|
|
|
NIH
Advisory Panels
|
Permanent
member, Bioorganic and Natural Products
Chemistry Study Section 1987-1991
|
|
NIH Ad hoc Reviewer for Moleular Structure and Function of Enzymes Study Section, June 2007 |
|
NIH Ad hoc Reviewer for Center for Scientific Review Special Emphasis Panel November 2005 |
|
NIH Ad hoc Reviewer for Macromolecular Structure and Function Study Section March 2005 |
|
National INstitutes of General Medical Sciences Advisory Council September 2002 |
|
NIH
Ad hoc Reviewer for Bioorganic & Medicinal Chemistry
Study Section Oct., 2001
|
|
NIH
Ad hoc Reviewer for Chemistry and Related Sciences
Study Section Nov., 1996
|
|
NIH
Ad hoc Reviewer for Medicinal Chemistry A Study
Section (AREA proposals) Nov., 1993
|
|
NIH
Special Reviewer for Bio-Organic and Natural
Products Chemistry Study Section Feb., 1987
|
|
NIH
Special Study Sections 12/83; 7/85
|
|
NIH Program Project Site Visits and Special Pharmacological
Sciences Review Committees:
 |
University
of Washington Feb., 1983
|
|
University
of Kansas June, 1981
|
|
|
| |
|
|
Conference
Organizer/Chair
|
Co-Chair,
Gordon Research Conference on Enzymes, Coenzymes,
and Metabolic Pathways 1994
|
|
Co-Vice
Chair, Gordon Research Conference on Enzymes,
Coenzymes, and Metabolic Pathways 1993
|
|
Organizer , 27th ACS Great Lakes Regional Meeting |
|
Organizer
of the entire program for the Division of Biological
Chemistry of the ACS Nat'l Meeting 2001
|
|
Organizer
and Chair, Symposium on Dual-Acting Drugs, ACS Nat'l Meeting
(DC) 2000
|
|
XVIII International Symposium on Medicinal Chemistry (Copenhagen, Denmark) 2004 |
|
Session
Chair, 5th Chemical Congress of North America Symposium
on NO Synthase Inhibitors 1997
|
|
Program
Committee, National Medicinal Chemistry Symposium
1996
|
|
Organizer
and Chairman of the 2nd, 14th and 26th Annual Midwest
Enzyme Chemistry Conference, Chicago 1982, 1994 and 2006
|
|
Organizer and Chairman of the Northwestern UniversityDepartment
of Chemistry Byron Riegel Lecture Series (Mechanism
of Action and Design of Drugs) 1980
|
|
|
Expert
Analyst for CHEMTRACTS 1988-1994
|
|
Special
Lectureships
|
Plenary
Lecturer, 4th Society of Chemical Industry-Royal
Society of Chemistry, Medicinal
Chemistry Symposium (Cambridge,
England) Sept., 1987
|
|
Plenary
Lecturer, 14th Scientific Sessions of the Rhone-Poulenc
Society (Lyon, France) Nov., 1991
|
|
Pew
Lecturer, Wheaton College (Wheaton, IL) Apr., 1992
|
|
Plenary
Lecturer, 20th Anniversary Marion Merrell Dow Research
Institute (Strasbourg, France) May, 1993
|
|
Peters
Lecturer, Virginia Polytechnic Institute and State University
(Blacksburg, VA) Oct., 1993
|
|
Burkett
Lecturer, DePauw University (Greencastle, IN) Apr., 1994
|
|
Teaching
faculty at the Residential School on Medicinal
Chemistry, Drew University
(Madison, NJ) 1995-present
|
|
Plenary
Lecturer, VII Meeting on Heterocyclic Structures
in Medicinal Chemistry (Mondello,
Sicily) May, 1996
|
|
Plenary Lecturer, University of Pennsylvania enzyme Symposium III (Philadelphia, PA) 1997 |
|
Plenary Lecturer, 40th Annual MIKI Meeting (Chicago, IL) 2002 |
|
Plenary Lecturer, Norwegian Organic Chemistry Winter Meeting (Roros, Norway) 2004 |
|
Frontier Science Lecturer, Wayne State University, Department of Chemistry (Detroit, MI) 2004 |
|
Plenary Lecturer, Science at the Interface of Chemistry and Biology, University of Notre Dame, Department of Chemistry and Biochemistry (South Bend, IN) 2004 |
|
Plenary Lecturer, International Conference on Chemistry Biology Interface: Synergistic New Frontiers (Dr. B.R. Ambedkar Center for Biomedical Research, New Delhi, India) 2004 |
|
Plenary Lecturer, IVth National Meeting on Medicinal Chemistry, (Caracas, Venezuela) 2007 |
|
Kilpatrick Lecturer, Illinois Institute of Technology (Chicago, IL) 2008 |
|
Plenary Lecturer, Royal Australian Chemical Institute, Division of Biomolecular Chemistry (Couran Cove, QLD, Australia) 2008 |
|
Ira Kukin Chemistry Lecturer, Yeshiva University (New York, NY) 2009 |
|
Plenary Lecturer, Canadian Society for Chemistry (Toronto, Ontario, Canada) 2010 |
|
|
Consultantships
|
Procter
and Gamble 1984
|
|
Abbott
Laboratories 1987
|
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Searle/Monsanto
1988-1990
|
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Leydig,
Voit & Mayer Law Offices 1992-present
|
|
DowElanco
1993-1995
|
|
Searle
& Co. 1995
|
|
Rohm
& Haas 1995
|
|
Affymax
1995
|
|
Kinetek
Pharmaceuticals 1999-
|
|
Guilford
Pharmaceuticals (Baltimore MD) 2001
|
|
ActivX
Biosciences (La Jolla, CA) 2001
|
|
Cytoclonal
Pharmaceutics (now eXegenics) (Dallas, TX) 2001
|
|
Hawaii Biotech, Inc. (Aiea, HI) 2003-2006
|
|
SynChem, Inc. (Des Plaines, IL) 2003-
|
|
|
Short
Courses Given:
|
"The
Organic Chemistry of Enzyme-Catalyzed Reactions"
|
E.I.
Du Pont de Nemours 9/91
|
|
Dow
Chemical Company 9/91
|
|
American
Chemical Society National Meeting (San
Francisco) 4/92
|
|
Indianapolis
Section of the American Chemical Society 12/92
|
|
American
Chemical Society National Meeting (Chicago) 8/93
|
|
Procter
& Gamble Pharmaceuticals 11/94
BioChem Pharma, Inc. 4/99
|
|
|
"The
Organic Chemistry of Drug Design and Drug Action"
|
American
Chemical Society National Meeting (Anaheim) 4/95
|
|
American
Chemical Society National Meeting (Chicago) 8/95
|
|
Western
Regional American Chemical Society Meeting
(San Diego) 10/95
|
|
American
Chemical Society (Somerset, NJ) 11/95
|
|
American
Chemical Society (New Orleans, LA) 3/96
|
|
American
Chemical Society (Orlando, FL) 8/96
|
|
American
Chemical Society (Boston, MA) 12/96
|
|
American
Chemical Society (San Francisco, CA) 4/97
|
|
American
Chemical Society (Philadelphia, PA) 4/97
|
|
Bayer
Pharmaceuticals (West Haven, CT) 5/97
|
|
American
Chemical Society (Las Vegas, NV) 9/97
|
|
American
Chemical Society (Dallas, TX) 4/98
|
|
Pharmaceutical
Ingredients Society (Philadelphia, PA) 5/98
|
|
St.
Louis Section of ACS 5/98
|
|
American
Chemical Society (Boston, MA) 8/98
PITTCON (Orlando, FL) 3/99
|
|
American
Chemical Society (Anaheim, CA) 3/99
|
|
Eli
Lilly and Co. (Indianapolis, IN) 6/99
|
|
Drug
Discovery Technology '99 (Boston, MA) 8/99
|
|
American
Chemical Society (New Orleans, LA) 8/99
|
|
WorldPharm
'99 (Philadelphia, PA) 10/99
|
|
San
Francisco (c/o ACS) 12/99
|
|
Hoffmann-La
Roche (Nutley, NJ) 12/99
|
|
Pittcon
(New Orleans, LA) 3/00
|
|
Bayer
(Kyoto, Japan) 3/00
|
|
AstraZeneca
(St. Laurent, Quebec, Canada) 6/00
|
|
Sphinx
Pharmaceuticals (Research Triangle Park, NC) 6/00
|
|
Drug
Discovery Technology 2000 (Boston, MA) 8/00
|
|
American
Chemical Society (Washington, DC) 8/00
|
|
Bristol-Myers
Squibb (Wallingford, CT) 9/00
|
|
American
Chemical Society (San Diego, CA) 4/01
|
|
Bristol-Myers
Squibb (Princeton, NJ) 7/01
|
|
Drug
Discovery Technology 2000 (Boston, MA) 8/01
|
|
American
Chemical Society (Chicago, IL) 8/01
|
|
American
Chemical Society (San Francisco, CA) 12/01
|
|
New York Police Department (Jamaica, NY) 3/02
|
|
American Chemical Society (Orlando, FL) 4/02
|
|
American Chemical Society (Boston, MA) 8/02
|
|
American Chemical Society (Boston, MA) 11/02
|
|
American Chemical Society (San Francisco, CA) 12/02
|
|
PPD Discovery (Morrisville, NC) 12/02
|
|
American Chemical Society (New Orleans, LA) 3/03
|
|
Drug Discovery Technology 2003 (Boston, MA) 8/03
|
|
American Chemical Society (New York, NY) 9/03
|
|
Bristol-Myers Squibb (Wallingford, CT) 6/03
|
|
American Chemical Society (San Francisco, CA) 12/03
|
|
American Chemical Society (Anaheim, CA) 3/04
|
|
Gilead Pharmaceuticals (Mountain View, CA) 4/04
|
|
Pfizer Pharmaceuticals (San Diego, CA) 4/04
|
|
Procter & Gamble (Cincinnati, OH) 5/04
|
|
Bristol-Myers Squibb (Princeton, NJ) 6/04
|
|
American Chemical Society (Philadelphia, PA) 8/04
|
|
American Chemical Society (San Diego, CA) 3/05
|
|
American Chemical Society (Washington, DC) 8/05
|
|
Encysive Pharmaceuticals (Houston, TX) 11/05 |
|
American Chemical Society (San Francisco, A) 9/06 |
|
IVth National Meeting on Medicinal Chemistry (Caracas, Venezuela) 6/07 |
|
|
|
Inclusion
in International Biographical Texts:
|
Who's
Who in Frontiers of Science and Technology 1984, 1985
|
|
International
Who's Who of Contemporary Achievement 1985
|
|
Who's
Who in the Midwest 1986-1988, 1991
|
|
Personalities
of America 1986
|
|
Who's
Who in Society 1986, 1988
|
|
Men
of Achievement 1986
|
|
Who's
Who of Emerging Leaders in America 1987
|
|
Who's
Who in America 1988-2010
|
|
Who's
Who in American Education 1994-2008
|
|
Who's
Who in Science and Engineering 1996-2008
|
|
Who's Who Among American's Teachers 2000 |
|
|
Advisory
Board Member, Illinois Mathematics and Science Academy 1988
|
|
Honorary
Member of the Golden Key National Honor Society 1994
|
|
Selection
Committee for the Division of Medicinal Chemistry Award 1998
|
|
Ad
hoc reviewer for the following journals: Science, J. Am. Chem.
Soc., Biochemistry, J. Biol. Chem., J. Org. Chem., J. Med. Chem.,
Arch. Biochem. Biophys., J. Neurochem., Mol. Toxicol., Can.
J. Chem., Biochim. Biophys. Acta, Biochem. Internat., Bioorg.
Chem., Biochem. Pharmacol., Chem. Res., Toxicol.,
Eur. J. Med. Chem., Mol. Pharmacol., Bioorg. Med. Chem. Lett.,
Tetrahedron, Int. J. Peptide Protein Res., Bioorg. Med. Chem.,
Angew. Chem. Int. Ed. Engl., Tetrahedron Lett., Synlett, Int.
J. Biochem. Cell Biol., Med. Chem. Res., J. Heterocycl. Chem.
|
|
Ad
hoc reviewer for the following books: American Chemical Society,
Division of Medicinal Chemistry and Division of Agrochemicals,
Encyclopedia of Chemical Technology
|
|
Ad
hoc reviewer for the following funding agencies: National Science
Foundation, Office of Naval Research,
Petroleum Research Fund, Research Corporation, National Research
Council (Canada), Human Frontier Science Program, Amherst College
Research Fund, US Department of Agriculture, North Carolina
Biotechnology Center, NSERC, The Wellcome Trust
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