My group’s interests overlap chemistry, biology and engineering, with an emphasis on the design and synthesis of materials that are biologically active and in applications of the materials to relevant problems in the biological and medical sciences.  Much of our work is focused on developing tools that can profile the full range of chemical reactions that occur in the cell, and that reveal the design principles that underlie the complex functions that they control.  Our group is jointly appointed through the departments of Biomedical Engineering, Chemistry, and Cell & Molecular Biology which is evident by the array of projects we are currently investigating.   Current work includes:

• Self-Assembled Monolayers for Biochemical Analysis
• Self-Assembled Monolayers for Matrix-Assisted Laser Desorption/Ionization (SAMDI) MS
• Biochip Assays for Drug Discovery
• Exracellular Matrix Micmics for Cellular Adhesion, Structure, and Dynamics
• Molecular Logic of Histone Modification
• Glycosyltransferase Discovery
• Assembly of Megamolecules
• Spatio-Temporal Control Over Biochemistry

Look on our Media page to see videos of Dr. Mrksich's research talks.

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2145 Sheridan Road

B490 Technolgical Institute

Evanston IL 60208