Our research is directed toward understanding the relationship between the unique structure of DNA and its interaction with light.
The foundation for these studies is the design, synthesis, and characterization of short stable DNA base pair domains. Incorporation of organic chromophores either at the ends or within the interior of synthetic DNA hairpins and dumbbells permits study of the dynamics and efficiency of photoinduced electron transfer, energy transfer, and exciton coupling – all of which are mediated by the helical, π-stacked base pair domain.
Our research benefits from extensive collaboration with physical and theoretical chemists interested in the behavior of DNA.
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